导航： 66文免费论文库 >> 医学 >> Life-Threatening Reactions with Ionic Contrast Medium: A Six-Year Experience
人体对注入血管的显影剂，会有某些相当严重的反应。在我们的伍仟肆佰参拾壹个病人中发生可致命反应的有五个例子占0?09%；较显著的如：血管陷落性循环不足、心跳停止、急性心肌梗塞，及过敏性休克。60%可急救成功。致死的有二个例子占0?037%其中一病例在注射显影剂的当时即狞死，另一病例在急救成功后至加护病房三天后死亡。显影剂引起的致命反应通常並无先兆，反应开始的愈早，急救的成功率愈低。而在使用显影剂前之测试是不可靠且多余的。一般说来致命的反应较易发生在七十岁以上，併有心肺功能不足的老人。所以非离子性显影剂对於年长的、心肺不足的及有过敏病史的病人特别適用。
Serious reactions to intravascular contrast medium are described. Predominant findings were vascular collapse, asystole, acute myocardial infarction and anaphylactoid reaction. The incidence of life-threatening reactions was 5 out of 5431 cases or 0.09%. The highest incidence, was in the 70-year-old group. Immediate successful resuscitation rate was 80%; overall successful resuscitation is 60%. Fatal reactions to contrast medium occur often without warning, and the earlier the reaction occurs, the less likelihood of successful resuscitation. The mortality rate was 2/5431 cases, or 0.037%. One patient died immediately during contrast administration, while another developed serious reaction during the contrast injection but death was delayed for three days with intensive medical treatment. Elderly patients with cardiopulmonary compromise status are most susceptible. For this reason, it is recommended that nonionic contrast medium be used for elderly patients, for the high risk group with cardiopulmonary disorders or for patients with a history of allergy.
